Structural and functional analysis of the huge compound produced by the dinoflagellate

2014 Fiscal Year Final Research Report

• Project/Area Number: 25810096
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Bio-related chemistry
• Research Institution: Gifu University
• Principal Investigator: INUZUKA Toshiyasu 岐阜大学, 生命科学総合研究支援センター, 助教 (50467271)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 渦鞭毛藻 / 巨大分子 / ポリオール / NMR / 質量分析 / 構造解析 / 分解反応

Outline of Final Research Achievements

A huge molecule, SCC5148, produced by the dinoflagellate Amphidinium sp. was isolated and analyzed its partial structure. Some partial structures of SCC5148 were revealed by the 2D-NMR spectra. Degradation reaction of SCC5148 gave many segments, and one of them was determined its structure. Additionally, novel huge molecules, amdigenols E and G, produced by the same dinoflagellate were isolated and determined their structures with 2D-NMR spectra and MS/MS analyses. Amdigenols have the common partial structures, and the some NMR signals of amdigenols were similar to those of SCC5148. This extrapolates that SCC5148 have the partial structures of amdigenols.

Free Research Field

天然物化学