2016 Fiscal Year Final Research Report
Cell monitoring system for the construction of three-dimensional organ in the tissue engineering
| Project/Area Number |
25820093
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Aichi Institute of Technology |
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Principal Investigator |
Yamada Akira 愛知工業大学, 工学部, 准教授 (20377815)
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| Research Collaborator |
NARUSE Keiji
MOHRI Satoshi
MATSUURA Koji
TERAMOTO Akira
MIURA Tsuyoshi
WAKUDA Akihiko
NOBUKUNI Masashi
SASAKI Yuta
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 再生医療 / ISFET / pH / pH-FET |
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| Outline of Final Research Achievements |
We have developed a monitoring system for the observation and evaluation of the growing condition for the precursor tissue that is transplanted into the patients. We constructed a tissue monitoring system in conjunction with a micro camera and pH/PCO2 sensor. The camera was used for the evaluation of cell morphology. The pH/PCO2 sensor was used for the evaluation of the quantity of respiration of the cell or tissue. During this development, we especially constructed a amplifier for the sensor and a software for PC to control the measurement system. We have also investigated the liquid junction problem which was problematic under the measurement of pH values. The liquid junction produce a voltage that are called a liquid junction potential and cause a measurement error. We have investigated to this point by constructing a special device based on microfluidics.
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| Free Research Field |
生体工学
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