2015 Fiscal Year Final Research Report
Study for structure and function of botulinum hemagglutinin
| Project/Area Number |
25860320
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bacteriology (including mycology)
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| Research Institution | Tokyo University of Agriculture (2014-2015)
Okayama University (2013) |
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Principal Investigator |
Suzuki Tomonori 東京農業大学, 応用生物科学部, 助教 (90453836)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | Clostridium botulinum / 毒素複合体 / ボツリヌス毒素 / 血球凝集素 / タンパク質間相互作用 |
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| Outline of Final Research Achievements |
The large toxin complex (L-TC) produced by Clostridium botulinum is formed from neurotoxin and four non-toxic proteins. In particular, HA components appear to play a role in the transport of the TC across the intestinal epithelium. In this study, the binding regions between HA subcomponents were examined.
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| Free Research Field |
細菌学、生物化学
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