Measurement of gastrointestinal pH profiles by pH capsule

2014 Fiscal Year Final Research Report

• Project/Area Number: 25860506
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine(including psychosomatic medicine)
• Research Institution: Yokohama City University
• Principal Investigator: IIDA HIROSHI 横浜市立大学, 医学部, 助教 (80600204)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 小腸 / pH

Outline of Final Research Achievements

We invented the novel device named “pH capsule” which noninvasively record both sequential images and pH within the gastrointestinal tract （Iida H, et al. A new non-invasive modality for recording sequential images and the pH of the small bowel. Hepatogastroenterology 2011;59:114）. The aim of this study was to investigate the pH changes from the terminal ileum to cecum by using the “pH capsule”.
Evans D F reported the measurement of gastrointestinal pH profiles in normal ambulant human subjects by using pH sensitive radiometry capsule in 1988 （Evans D F et al. Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut 1988;29:1035-41）.
We confirmed by using "pH capsule" that the pH in the normal gastrointestinal increase in pH from the duodenum to the terminal ileum, decrease in the cecum.

Free Research Field

消化管