2014 Fiscal Year Final Research Report
The role of cytokines in the pathophysiology of autism and depression
| Project/Area Number |
25860997
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 自閉症スペクトラム / サイトカイン / 認知機能 |
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| Outline of Final Research Achievements |
Evidence indicates that immune system and nervous system reciprocally regulate each other through cytokines. Previous reports have shown that some cytokines are increased in patients with autism spectrum disorder (ASD). In the present study, we showed that children with ASD who had higher blood levels of interleukin-6 (IL-6) had lower verbal comprehension scores. This finding suggests the possibility that IL-6 may play a role in the impairment of cognitive development in those with ASD.
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| Free Research Field |
精神医学
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