2014 Fiscal Year Final Research Report
Pulse near-infrared light irradiation study in the depression
| Project/Area Number |
25861021
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Oita University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | うつ病 / 近赤外線光 / うつ病動物モデルラット / 効果十字迷路試験 / 明暗箱試験 / 恐怖条件付け試験 |
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| Outline of Final Research Achievements |
As for the cure for depression, medical therapy and psychotherapy are important. Depression patients increased and considered treatment by near-infrared light as a cure in the future depression. I performed near-infrared light irradiation to a head and, using uneasiness and a depression animal model rat, confirmed presence of the antianxiety antidepressant action. I divided a rat into two groups and irradiated 5-minute near-infrared light consecutively in the irradiation group on a day for two weeks. I performed an elevated cross maze examination, a light camera examination, a fear conditioning examination to each rat and examined the difference of the antianxiety effect between control group and the irradiation group afterwards.The subacute pulse near-infrared light radiation significantly inhibited anxiety and depression in anxiolytic and depressive animal model rat. In addition, this significantly increased the neurogenesis in the rat hippocampus.
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| Free Research Field |
うつ病
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