Continuity between schizophrenia and mood disorders: a comprehensive investigation of genes, cognition and schizotypal traits

2014 Fiscal Year Final Research Report

• Project/Area Number: 25861041
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Psychiatric science
• Research Institution: National Center of Neurology and Psychiatry
• Principal Investigator: HORI Hiroaki 独立行政法人国立精神・神経医療研究センター, 精神保健研究所 成人精神保健研究部, 室長 (10554397)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 統合失調症 / 気分障害 / 統合失調型パーソナリティ / 認知機能 / 遺伝子多型

Outline of Final Research Achievements

We examined continuity and discontinuity between schizophrenia and mood disorders by investigating candidate gene variants, comprehensive cognitive functioning and personality characteristics in patients with schizophrenia, those with mood disorders and healthy control subjects. We have conducted a set of studies and obtained results suggesting genetic similarities between the two disorders. These results are considered to advance findings from relevant studies and contribute to elucidating the pathogenesis of schizophrenia and mood disorders.

Free Research Field

精神神経科学