Clinical application and development of Q-space imaging analysis software using multi shot echo-planar imaging sequence

2015 Fiscal Year Final Research Report

• Project/Area Number: 25861083
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Nagoya University
• Principal Investigator: Fukuyama Atsushi 名古屋大学, 医学(系)研究科(研究院), 助教 (40452198)
• Research Collaborator: ISODA Haruo 名古屋大学, 脳とこころの研究センター, 教授 (40223060) ; KOMORI Yoshiaki シーメンスヘルスケアジャパン株式会社 ; IWASE Daisuke 刈谷豊田総合記念病院, 診療放射線技師
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: MRI / Q-space imaging / 拡散解析 / 拡散強調画像 / 画像歪み / Multi Shot EPI / RESOLVE / 非ガウス分布解析

Outline of Final Research Achievements

The purpose of this study was to examine the usefulness of Q-space image analysis (specifically diffusion kurtosis imaging) by using diffusion-weighted images obtained from multi-shot echo planar imaging (EPI) sequences. The results confirm that fewer images were obtained from multi-shot EPI sequences than from single-shot EPI sequences. Furthermore, there were no significant differences in apparent diffusion coefficient (ADC) or diffusion kurtosis values. Multi-shot EPI sequences have a tendency to extend acquisition time; however, it is possible to acquire images with high spatial resolution and less distortion. In conclusion, this method is clinically significant.

Free Research Field

放射線科学