2014 Fiscal Year Final Research Report
Antitumor effect of transcatheter arterial embolization in combination with sorafenib in a rabbit VX2 liver tumor model
| Project/Area Number |
25861084
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
TOMOZAWA Yuki 滋賀医科大学, 医学部, 助教 (90585689)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | ソラフェニブ / 肝動脈塞栓 |
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| Outline of Final Research Achievements |
Using a VX2 liver tumor model, we investigated antitumor effect of the combination of TACE with sorafenib and suitable timing parameters when using sorafenib to enhance the anti-tumor effects of TAE. In conclusion, we suggest that a combination of sorafenib with TAE is a more effective treatment than sorafenib or TACE alone and the ideal time of TAE is prior to or early after commencement of administration Sorafenib.
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| Free Research Field |
腹部画像診断・IVR
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