2015 Fiscal Year Final Research Report
Establishment of a cancer diagnosis method using DNA increase derived from plasma tumor after the radiation therapy
| Project/Area Number |
25861145
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Tokyo Metropolitan Komagome Hospital (Clinical research laboratory) |
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Principal Investigator |
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| Research Collaborator |
Karasawa Katsuyuki 都立がん・感染症センター駒込病院, 放射線診療科, 部長 (80177617)
Nihei Keizi 都立がん・感染症センター駒込病院, 放射線診療科, 医長 (30466205)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 放射線治療 / cfDNA / 遺伝子診断 |
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| Outline of Final Research Achievements |
It was possible in this study to increase DNA derived from blood tumor to 2 times - around 30 times by the radiation exposure for the cancer tissue.
Our result indicate that cfDNA analysis after palliative radiation therapy could provide genotype informatin in radiotherapy treated cite tumor.
Cf DNA analysis after radiotherapy would be potential option in future cancer therapy.
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| Free Research Field |
放射線生物学
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