clarification of human bladder smooth muscle and application to new treatment of lower urinary tract dysfunction

2015 Fiscal Year Final Research Report

• Project/Area Number: 25861433
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Urology
• Research Institution: Fukushima Medical University
• Principal Investigator: Ogawa Soichiro 福島県立医科大学, 医学部, 助教 (50554200)
• Co-Investigator(Kenkyū-buntansha): ISHIBASHI Kei 福島県立医科大学, 医学部泌尿器科学講座, 准教授 (90347211) ; YABE Michihiro 福島県立医科大学, 医学部泌尿器科学講座, 助手 (30745782) ; AKAIHATA Hidenori 福島県立医科大学, 医学部泌尿器科学講座, 助手 (70644178) ; HATA Junya 福島県立医科大学, 医学部泌尿器科学講座, 助手 (00769606)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: Kチャネル / 膀胱 / 弛緩

Outline of Final Research Achievements

Overactive bladder decreases the patients' quality of life. Thus, it is important for us to elucidate the pathophysiology of overactive bladder.
We have demonstrated that human bladder smooth muscle does not always relax through cAMP-dependent pathway. Furthermore, we have shown that these pathway does not involved in K channels.

Free Research Field

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