2014 Fiscal Year Final Research Report
Identification of genes associated with the development of organ lesions in sarcoidosis
| Project/Area Number |
25861643
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Yokohama City University |
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Principal Investigator |
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| Research Collaborator |
MIZUKI Nobuhisa
MEGURO Akira
SATO Mayuki
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | サルコイドーシス / 遺伝子 |
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| Outline of Final Research Achievements |
Sarcoidosis is a chronic systemic disease characterized by the accumulation of non-caseating granulomas in a wide range of organs such as lungs, lymph nodes, eye, skin and heart. The etiology of sarcoidosis is still uncertain, but the disease is currently thought to be triggered by various genetic as well as environmental factors.
In this study, we investigated genetic factors associated with each organ legion in sarcoidosis using a genome-wide association study data in a Japanese population and identified several genes that may contribute to the development of each organ legion.
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| Free Research Field |
眼科学
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