Change in infected root canal microflora during the course of root canal therapy

2016 Fiscal Year Final Research Report

• Project/Area Number: 25861785
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Conservative dentistry
• Research Institution: Tohoku University
• Principal Investigator: Hashimoto Kazuhiro 東北大学, 歯学研究科, 大学院非常勤講師 (70646447)
• Research Collaborator: SATO TAKUICHI 新潟大学, 医歯学系, 教授 (10303132)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 歯学 / 細菌 / 感染根管 / 細菌叢 / メタゲノム / PCR

Outline of Final Research Achievements

Obligate anaerobes have been reported to comprise the majority of oral biofilm including intracanal-microbiota. The bacterial profiling of infected root canals has been long performed. In the present study, metagenomic analysis was applied to the profiling of microbiota in infected root canals, and detailed components of the microbiota of infected root canals were found utilizing high-speed sequencers without random-cloning.

Free Research Field

歯科保存学