2014 Fiscal Year Final Research Report
Role of HAI-1 and TTSP in Ameloblastoma
| Project/Area Number |
25861961
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | University of Miyazaki |
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Principal Investigator |
BABA Takashi 宮崎大学, 医学部, 助教 (70626051)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | エナメル上皮腫 |
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| Outline of Final Research Achievements |
HAI-1 expression knock-down (KD) in immortalized ameloblastoma cell lines, AM-1 and AM-3, reduced the growth of both lines in vitro. Both HAI-1 KD cell lines also exhiboted significantly enhanced migratory capability.
In 85.7% (12/14) of Ameloblastoma cases, membranous HAI-1immunoreactivity was positive in tumor cells.
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| Free Research Field |
口腔外科
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