2015 Fiscal Year Final Research Report
Exhaustive analysis of nonsyndoromic Oligodoitia in multiple Japanese families
Project/Area Number |
25861996
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Orthodontics/Pediatric dentistry
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Research Institution | Hokkaido University |
Principal Investigator |
KIDA MIYUKI 北海道大学, 医学(系)研究科(研究院), 客員研究員 (80507442)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | 遺伝性非症候性多数歯欠損症 / 網羅的解析 / 遺伝子解析 |
Outline of Final Research Achievements |
Oligodontia designates the congenital absence of 6 or more permanent teeth, excluding the third molar. I investigated three Japanese families with nonsyndoromic Oligodontia. All affected members in three families were revealed very severe Oligodontia phenotype clinically, number of missing teeth of them were over 10. The early diagnosis and decision on courses of treatment are very important for patients with nonsyndoromic Oligodontia to maintain their quality of life. The aim of the present study revealed the candidate gene of nonsyndoromic Oligodontia and unique SNPs
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Free Research Field |
医歯薬学
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