2014 Fiscal Year Final Research Report
Elucidation of the Novel Phosphorylase-Dependent Metabolisms of Glycosonjugates and Lipopolysaccharides
| Project/Area Number |
25892011
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Keywords | 微生物酵素 / 糖質 / ホスホリラーゼ |
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| Outline of Final Research Achievements |
Three novel β-mannoside phosphorylases (β-1,4-mannosyl-N-acetylglucosamine phosphorylase, β-1,2-mannbiose phosphorylase and β-1,2-oligomannan phosphorylase) were characterized as new member of glycoside hydrolase family 130 from Bacteroides thetaiotaomicron and Thermoanaerobacter sp. X-514. We further suggested that these β-mannoside phosphorylases play crunical roles in metabolisms of N-glycans or beta-1,2-oligomannan.
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| Free Research Field |
応用微生物学
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