Analysis of hemostasis of aged trauma patients and investigation for noble biomarker related to hemostasis

2014 Fiscal Year Final Research Report

• Project/Area Number: 25893016
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Emergency medicine
• Research Institution: Tohoku University
• Principal Investigator: KUDO Daisuke 東北大学, 医学(系)研究科(研究院), 助教 (30455844)
• Project Period (FY): 2013-08-30 – 2015-03-31
• Keywords: 外傷 / 凝固 / 止血

Outline of Final Research Achievements

Actual ability of hemostasis can be measured by Rotation Thromboelastometry [ROTEM delta Tem (International GmbH)] examination. Correlation between actual ability of hemostasis and common coagulation markers was investigated in the patients with severe trauma. Seven (43.8%) of 16 patients who showed normal range of coagulation markers, represented decreased ability of hemostasis by ROTEM examination. Five of 7 had severe brain injury and included both young and old patients.
These results showed that it is difficult to evaluate ability to hemostasis not only by the common coagulation markers. Further investigation is required to effectiveness of ROTEM examination on outcome in the patients with severe trauma.

Free Research Field

救急医学