2014 Fiscal Year Final Research Report
Significance of Muscularis Mucosae Invasion in Early Gastric Cancer
Project/Area Number |
25893191
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Human pathology
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Research Institution | Kagoshima University |
Principal Investigator |
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Project Period (FY) |
2013-08-30 – 2015-03-31
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Keywords | 早期胃癌 / 粘膜筋板 / ムチン抗原 / 内視鏡的切除 |
Outline of Final Research Achievements |
In early gastric cancers, there is no discrimination between (1) the case with intramucosal proliferation showing no muscularis mucosae invasion (abbreviated as “pT1a1-M” ) and (2) the case with intramucosal proliferation showing muscularis mucosae invasion (abbreviated as “pT1a2-MM” ). Both of them are classified into the same depth invasion criteria, abbreviated as pT1a (M), not only in UICC but also in the Japanese Classification of Gastric Carcinoma. In the present study, “pT1a2-MM” showed higher rates of vessel permeation, lymph node metastasis, and the positive MUC1/DF3 expression than “pT1a1-M”. Therefore “pT1a1-M” and “pT1a2-MM” should be divided.
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Free Research Field |
医歯薬学
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