2017 Fiscal Year Final Research Report
Mechanisms for neuroblast migration in the maintenance and regeneration of postnatal brain tissue
Project/Area Number |
26250019
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Research Category |
Grant-in-Aid for Scientific Research (A)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Neurochemistry/Neuropharmacology
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Research Institution | Nagoya City University |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
KANEKO Naoko 名古屋市立大学, 大学院医学研究科, 講師 (20464571)
SAWADA Masato 名古屋市立大学, 大学院医学研究科, 助教 (20645288)
|
Research Collaborator |
JINNOU Hideo
FUJIKAKE Kazuma
FUJIOKA Teppei
|
Project Period (FY) |
2014-04-01 – 2018-03-31
|
Keywords | 再生医学 / 神経科学 / 脳・神経 / 脳神経疾患 |
Outline of Final Research Achievements |
We have studied 1) the expression and function ofβ1integrin in migrating neuroblasts for their efficient chain migration along the blood vessel scaffolds, 2) morphological changes of neuroblasts during migration termination and their molecular mechanisms, 3) olfactory-input dependent mechanisms for neuronal integration and maturation, and 4) neuronal regeneration and functional recovery promoted by neuronal migration.
|
Free Research Field |
再生医学
|