Development of tooth regeneration technology based on the clarification of mechanism of tooth development.

2017 Fiscal Year Final Research Report

• Project/Area Number: 26253088
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Okayama University
• Principal Investigator: Kuboki Takuo 岡山大学, 医歯薬学総合研究科, 教授 (00225195)
• Co-Investigator(Kenkyū-buntansha): 大島 正充 岡山大学, 医歯薬学総合研究科, 助教 (00548307) ; 辻 孝 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, チームリーダー (50339131) ; 大野 充昭 岡山大学, 医歯薬学総合研究科, 助教 (60613156) ; 淺原 弘嗣 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (70294460) ; 秋山 謙太郎 岡山大学, 大学病院, 講師 (70423291) ; 内部 健太 岡山大学, 医歯薬学総合研究科, 助教 (20584618)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 歯の再生 / 器官原基法

Outline of Final Research Achievements

Whole-tooth regeneration therapy has great potential for the replacement of lost teeth．Recently, our group have been reported an in vitro three-dimensional cell manipulation method called the bioengineered organ germ method. However, it is unclear the mechanism of tooth development. Therefore, we performed the comprehensive analysis and could narrow down the several candidate genes. In the future, we are planing to perform the functional analysis of these candidate genes.

Free Research Field

歯科補綴学