Multidisciplinary Approach for Arteriovenous Malformation Based on Computational Fluid Dynamics

2016 Fiscal Year Final Research Report

• Project/Area Number: 26282141
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Medical systems
• Research Institution: Akita University
• Principal Investigator: Shimizu Hiroaki 秋田大学, 医学(系)研究科(研究院), 教授 (20506638)
• Co-Investigator(Kenkyū-buntansha): 冨永 悌二 東北大学, 医学(系)研究科(研究院), 教授 (00217548) ; 新妻 邦泰 東北大学, その他の研究科, 助教 (10643330) ; 杉山 慎一郎 東北大学, 医学(系)研究科(研究院), その他 (30623152) ; 鷲尾 利克 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 (40358370) ; 大田 英揮 東北大学, 大学病院, 助教 (40586905) ; 荒船 龍彦 東京電機大学, 理工学部, 助教 (50376597) ; 船本 健一 東北大学, 学内共同利用施設等, 准教授 (70451630)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 脳動静脈奇形 / 数値流体力学 / 集学的治療 / 脳動脈瘤 / MRI / 脳血管撮影

Outline of Final Research Achievements

Hemodynamics of arteriovenous malformation (AVM) was successfully analyzed using computational fluid dynamics (CFD). Four dimensional magnetic resonance imaging (4D-MRI) was also performed and compared with CFD. Hemodynamic parameters such as wall shear stress and velocity were provide by both CFD and 4D-MRI. However patients who suffered from AVM mostly had severe physical conditions, and it was difficult to create a large database during three years.

On the other hand, the research team developed a new approach for diagnosing the risk factor of the recurrence after coil embolization of cerebral aneurysms. Based on it, a new software to evaluate the risk for coil embolization is under developing. In conclusion, this project became a foundation for the future development of CFD.

Free Research Field

脳血管障害