The solution of neuronal basis for long-term benefit of CI therapy and, construction of more beneficial treatment strategy for upper-extremity deficit in chronic stroke patients.

2017 Fiscal Year Final Research Report

• Project/Area Number: 26282158
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Hyogo Medical University
• Principal Investigator: Domen Kazuhisa 兵庫医科大学, 医学部, 教授 (50207685)
• Co-Investigator(Kenkyū-buntansha): 小山 哲男 兵庫医科大学, 医学部, 特別招聘教授 (40538237) ; 内山 侑紀 兵庫医科大学, 医学部, 助教 (50725992) ; 池田 紗綾香 兵庫医科大学, 医学部, 助教 (70751436) ; 高橋 香代子 北里大学, 医療衛生学部, 講師 (70572155) ; 友利 幸之介 長崎大学, 医歯(薬)学総合研究科, 研究員 (90381681) ; 古河 慶子 兵庫医科大学, 医学部, 助教 (10412016) ; 足立 清香 兵庫医科大学, 医学部, 助教 (70731694)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 脳卒中

Outline of Final Research Achievements

Deliverables of this study consist of 4 parts. First, We investigated on the nerve fiber related the long-term benefit of CI therapy. Consequently, we found 7 important nerve fivers involved the upper-extremity motor control and learning. Secondly, We developed the multiple intervention using robotic therapy, electrical stimulation therapy, and CI therapy for severe upper-extremity deficit. Consequently, we found that the multiple intervention significantly improved the paretic upper-extremity function. Thirdly, We developed the application termed "ADOC-H" to quantify of behavioral strategy involved the long-term benefit of CI therapy. Forth, we applied the fostered methodology(robotic therapy and electrical stimulation therapy) for upper-extremity deficit in a treatment of lower-extremity deficit. Consequently, two new treatments for lower-extremity deficit significantly improved the function or walking speed.

Free Research Field

脳卒中