Development of Functional Supramolecular Materials based on Metalated Amino Acids and Peptides

2016 Fiscal Year Final Research Report

• Project/Area Number: 26288036
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Functional solid state chemistry
• Research Institution: Kyoto University
• Principal Investigator: Takaya Hikaru 京都大学, 化学研究所, 准教授 (50304035)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: メタル化アミノ酸 / メタル化ペプチド / 自己組織化 / 超分子 / 金属配列制御 / 酸化反応 / Ru

Outline of Final Research Achievements

Precisely-controlled metal array fabrication can be achieved through the
self-assembly of metalated amino acids and related peptides, where the functionaltransition-metal complexes conjugate to the α-side chains of the amino acids. The chemically and physically robust transision-metal complex-bound amino acids allowed for controlled metal array fabrication on a nanometer-scale. Control of the metal sequence was accomplished by the condensation of through the chronological ordering of the amino acid condensation processes. The supramolecular-based self-assembly metalated peptides also gave rise to nanometer-scale regulated arrays. The resulting metalated amino acids and peptides were recently found to show excellent catalytic acitivity for various oxidation reations under aqueous conditions using H2O2 as an oxidant.

Free Research Field

有機化学，有機金属化学，ペプチド科学，超分子化学