Specificity of cold adaptation in human thermogenesis and multiple organs coordination

2017 Fiscal Year Final Research Report

• Project/Area Number: 26291099
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Applied anthropology
• Research Institution: Hokkaido University (2016-2017); Chiba Institute of Technology (2014-2015)
• Principal Investigator: WAKABAYASHI HITOSHI 北海道大学, 工学研究院, 准教授 (50452793)
• Co-Investigator(Kenkyū-buntansha): 金田 晃一 千葉工業大学, 先進工学部, 准教授 (10534589) ; 引原 有輝 千葉工業大学, 創造工学部, 准教授 (10455420) ; 栃原 裕 九州大学, 芸術工学研究院, 名誉教授 (50095907)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 寒冷適応 / 褐色脂肪細胞 / 骨格筋 / 寒冷誘発性代謝 / 皮膚血流

Outline of Final Research Achievements

This study investigated specificity of adaptation in human thermoregulatory response after repetitions of cold exposure which initiated different thermoregulatory response. Repeated local cooling of forearm muscle increased oxidative muscle metabolism during hand grip exercise. We investigated the relationship between thermoregulatory response in cold climate chamber and brown adipose tissue activity assessed using FDG-PET/CT. Additionally, we investigated the adaptation in the thermoregulatory response after repeated cold exposure which induced only non-shivering thermogenesis.

Free Research Field

環境生理学，環境人間工学