2016 Fiscal Year Final Research Report
Comprehensive molecular epidemiological study for parasites distributing in Indonesia
Project/Area Number |
26305008
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 海外学術 |
Research Field |
Parasitology (including sanitary zoology)
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Research Institution | Kanazawa University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
木村 憲司 金沢大学, 医学系, 研究員 (10572183)
吉川 尚男 奈良女子大学, 自然科学系, 准教授 (50191557)
伊藤 誠 愛知医科大学, 医学部, 教授 (90137117)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Keywords | インドネシア / 分子分類 / エントアメーバ / ジアルジア / 季節性 / 宿主因子 / 腸管寄生原虫 / 人獣共通感染 |
Outline of Final Research Achievements |
Seasonal molecular epidemiology of Entamoeba spp. and Giardia intestinalis was evaluated using children’s and related animal fecal samples at a rural village in Indonesia. The higher positive rate of E. coli in rainy season (23.9%, vs. 33.7%, P=0.02 in dry and rainy seasons respectively) was observed, and the main factor that brings about this was thought to be the higher E. coli prevalence (11.5% vs. 20.6%, P=0.02, same as the above) in female. While, the genotyping evaluation of G. intestinalis confirmed the lower prevalence of both assemblage A and B among female population in rainy season (A: 5.9% vs. 0.8%, P=0.026; B: 16.9%, vs. 7.8%, P=0.035, same as the above), though there was no seasonal difference of those prevalences in male. The comprehensive molecular screening approaches for those various species and genotypes could address environmental and host-related factors effectively.
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Free Research Field |
分子寄生虫学
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