2016 Fiscal Year Final Research Report
Brain Injury Biomechanics Research integrating its Spationtemporal Factors using Injury Reconstruction Technique and Neurortansmission Functional Evaluation
| Project/Area Number |
26350495
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 統合的傷害バイオメカニクス / 実症例再現実験 / 頭部実体モデル / 急性硬膜下血腫 / びまん性脳損傷 / 膜電位解析 / 脳実質ひずみ計測 |
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| Outline of Final Research Achievements |
Brain injury occurs as a consequence of human behavior, protective reaction, rigid body motion, tissue deformation and cell damage. In order to understand the spatiotemporal structure of injuries, we conducted integrated brain injury biomechanics researches regarding rigid body motion of the head, tissue deformation and cell damage. Especially, we focused on rotational brain injuries mechanisms such as diffused brain injuries and acute subdural haematoma. In order to clarify relationship between rigid body motion of the head and tissue damage, we conducted injury reconstruction experiments for child abuse, household trauma and sports injury in Judo, by using our original physical head models capable of visualization ofintracranial brain motion. In addition, in order to clarify relationship between tissue deformation and cell damage, we examined relationship between strain distribution and action potential when strain is loaded to corpus callosum of rat brain slice.
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| Free Research Field |
傷害バイオメカニクス
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