2016 Fiscal Year Final Research Report
Phase II cardiac rehabilitation in patients with heart failure due to cardiovascular diseases
| Project/Area Number |
26350585
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 心筋重量 / 下肢筋力 / 運動時血圧上昇 |
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| Outline of Final Research Achievements |
This study aimed to investigate relationships between muscle weakness, blood pressure (BP) elevation during exercise and left ventricular mass (LVM) in patients with hypertension. Eighty-six hypertensive patients aged 69 ± 8 years with controlled resting BP (i.e., <140/90 mmHg) were recruited. Left ventricular mass index (LVM) and knee extension muscle strength were measured. Difference between baseline and peak systolic BP during the ergometer exercise test was defined as BP elevation during exercise (ΔSBP). Muscle strength was negatively correlated with ΔSBP (r=-0.230, P=0.033) and LVMI (r=-0.233, P=0.031). LVMI was positively correlated with ΔSBP (r=0.307, P=0.033). Muscle strength was a significant independent factor associated with LVMI (β=-0.319, P=0.012). Our findings suggest that muscle weakness is associated with an increase of LVM through excessive BP elevation during exercise in patients with hypertension.
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| Free Research Field |
心臓リハビリテーション
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