The effect of reward system on neurogenesis and exercise

2016 Fiscal Year Final Research Report

• Project/Area Number: 26350697
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Developmental mechanisms and the body works
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: INOKAWA HITOSHI 京都府立医科大学, 医学(系)研究科(研究院), 講師 (40285250)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: ドーパミン

Outline of Final Research Achievements

It is becoming clear that exercise not only maintains physical activity level but also suppresses chronic diseases and has the effect of promoting neurogenesis in the central nervous system. In addition, it is becoming clear that the function of dopamine in basal ganglia is important for normal movement. It is also considered that there is a diurnal variation in dopamine release. Therefore, we examined whether the dopamine system and circadian rhythm affect neurogenesis, the relationship of spontaneous motor behavior and neurogenesis, and the regulation by circadian rhythm of dopamine. We are analyzing the relationship between spontaneous momentum and neurogenesis using immunostaining. There was also a tendency for dopamine release to have a difference in day and night.

Free Research Field

神経生理学