A Randomised Controlled Trial Investigating the Clinical and Cost-Effectiveness of Peer Enhanced-computerised Cognitive Depression:

2016 Fiscal Year Final Research Report

• Project/Area Number: 26350862
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied health science
• Research Institution: Institute of Wellness and Ecological Sciences (Global Research Center for Applied System Science)
• Principal Investigator: SO MIRAI 有限会社自然医科学研究所(実証システム国際研究センター), 実証システム国際研究センター, 研究員 (00327636)
• Co-Investigator(Renkei-kenkyūsha): WATANABE Norio 京都大学, 医学(系)研究科(研究院)・その他部局等, 准教授 (20464563)
• Research Collaborator: YAMAGUCHI Sosei ; SADO Mitsuhiro ; TAKEBAYASHI Yoshitake
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: Internet CBT / インターネット認知行動療法 / CBT / ICBT / CCBT / RCT / 認知行動療法 / 強化学習

Outline of Final Research Achievements

We evaluated the effectiveness of self-help internet-based cognitive behavioural therapy (iCBT) over ７ weeks among Japanese workers with depression (RCT). Also, we evaluated in parallel whether the weekly 10 minutes’ pair-work exercise by “talking to others” of what they learned through experiencing self-help iCBT enhance the effectiveness of standalone iCBT. The result was the standalone iCBT group showed a significant moderate-to-large improvement of depression, with an effect size of Hedge’s g = 0.65, compared to the waitlist group. On the other hand, there was no significant difference between the pair-work iCBT and the waitlist. There were different opinions on the pros and cons. Moreover, it was demonstrated that there was a marginally significant positive association between the number of pair-work exercises and the antidepressant efficacy only among those with higher anxiety at baseline (p=0.06). Due to the lack of the pair-work efficacy, there was no cost-effectiveness.

Free Research Field

認知行動療法