2016 Fiscal Year Final Research Report
A layer structure map of the monkey frontal-lobe by current source density analysis using multi-contact electrode
| Project/Area Number |
26350991
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Brain biometrics
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MUSHIAKE Hajime 東北大学, 医学系研究科, 教授 (80219849)
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| Research Collaborator |
KAWAGUCHI Norihiko 東北医科薬科大学, 医学部, 助教
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | サル / 前頭前野 / 運動前野 / LFP / 電流源解析 / 形操作課題 |
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| Outline of Final Research Achievements |
Current source (CSD) analysis was performed on the local field potential (LFP) recorded with a multi-contact electrode from the monkey lateral prefrontal cortex (lPFC) and the dorsal premotor area (PMd) while executing a shape manipulation task. In the lPFC, a current sink, considered to be an excitatory synaptic input, was observed in the deep layer just before the first visual stimulus (sample stimulus) was presented. It was also found that this current sink corresponds to a transient α-θ-δ wave (13 - 3 Hz) component. On the other hand, in the PMd, current sink was seen in the middle layer during the second visual stimulus (test stimulus) presentation period. This component was correlated with a persistent low beta wave (<20 Hz). These results would greatly contribute to elucidating the dynamics of the local circuits and the functional differentiation of the two areas.
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| Free Research Field |
システム神経生理学
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