2016 Fiscal Year Final Research Report
Mathematics of cell adhesion: experiments, modeling and analysis
| Project/Area Number |
26400205
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Foundations of mathematics/Applied mathematics
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 応用数学 / 数値解析学 / 数理生物学 / 細胞・組織 / 細胞接着 / 細胞選別 / 数理モデル |
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| Outline of Final Research Achievements |
Cell adhesion is one of the most important phenomena in the life science. The aim of this research was to construct mathematical base for elucidating the cell adhesion phenomenon. To this end, we conducted experiments, modeling and analysis comprehensively. According to experiments, cell proliferation rate, carrying capacity, adhesion strengths etc. were measured actually. Based on the experiment, we constructed a mathematical model and carried out numerical experiments. As a result, it was found that our model can replicate various phenomena related to cell adhesion qualitatively and quantitatively. Furthermore, we analyzed the basic properties of the mathematical model from the mathematical point of view. In addition, we applied it to elucidation of an actual phenomenon in life science.
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| Free Research Field |
数物系科学
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