2016 Fiscal Year Final Research Report
Effects of rare earth ions on biological systems
| Project/Area Number |
26420718
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Iwate University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 希土類金属 / 抗菌活性 / 抗カビ活性 / 抗線虫活性 / 金属ストレス / ストレス応答 |
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| Outline of Final Research Achievements |
Despite the name, rare earth elements are relatively abundant in soil. Therefore, these elements might interact with biosphere during the history of life. In this study, we have examined the effect of rare earth ions on the growth of bacteria, fungi, and soil nematode. All rare earth ions, except radioactive promethium that we have not tested, showed antibacterial and antifungal activities comparable to that of copper ions, which is widely used as antibacterial metals in our daily life. Since the rare earth ions did not show high toxicity to the human lymphoblastoid cell line or even stimulated the growth of the cultured cells at 1 mM, raising the possibility that we can substitute rare earth elements for the antibacterial metals usually used because of their safety.
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| Free Research Field |
分子遺伝学 分子生物学
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