2016 Fiscal Year Final Research Report
Development of the novel in vivo model for acute coronary syndrome
| Project/Area Number |
26430089
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Laboratory animal science
|
|---|
| Research Institution | Kobe University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 急性冠症候群 / 疾患モデル / 冠動脈硬化 |
|---|
| Outline of Final Research Achievements |
Acute coronary syndrome (ACS) is a life-threaten disease for mainly middle-aged men. Although prevention of ACS is one of the most important task for human beings, a lack of an appropriate animal model for this disease is a barrier for the development of its prevention. We tried to develop the animal model for ACS and we’ve established the experimental model for mimicking the initiation of ACS, i.e., coronary plaque injury, in the coronary arteries of live animals. It is expected that this model may contribute to the evaluation of novel drugs for prevention of ACS.
|
| Free Research Field |
実験動物学
|
