2017 Fiscal Year Final Research Report
Bacteriological and epidemiological studies for elucidating the pathophysiology of bovine digital dermatitis and its control
| Project/Area Number |
26450406
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Veterinary medical science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MISAWA Naoaki 宮崎大学, 産業動物防疫リサーチセンター, 教授 (20229678)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | 牛 / 趾乳頭腫症 / 生菌製剤 / 抗生物質 / Treponema属菌 / 細菌叢解析 / リアルタイムPCR / LAMP |
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| Outline of Final Research Achievements |
The possibility of preventing the recurrence of bovine digintal dermatitis (PDD) and re-infection of Treponema species was demonstrated by using the combined treatment of application of allyl isothiocyanate (AITC) and hoofing. Microbiome analysis indiated that T. medium-like and T. denticola-like isolates showed the possibility of playing an important role in PDD deformity. We developed three real-time PCR and four LAMP assays that can specifically detect and distinguish three different Treponema species at both genus and species levels.
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| Free Research Field |
獣医学
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