2016 Fiscal Year Final Research Report
Development of a method for measuring HHV-6A and HHV-6B specific antibodies using synthetic peptides
| Project/Area Number |
26460661
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Fujita Health University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | HHV-6A / HHV-6B / ELISA / 合成ペプチド / 抗体測定法 |
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| Outline of Final Research Achievements |
The clinical feature and seroepidemiology of HHV-6A remain unclear. Establishment of a species-specific serological test method is indispensable from the characteristics of the latent infectious herpes virus group. Therefore, we aimed to establish an antibody measurement system by ELISA using species-specific synthetic peptides.
Based on our results of this time, we could not obtain superior results from seven of the HHV-6A synthetic peptides. In HHV-6B, the HHV-6B 1 synthetic peptide gave the best results but it was unsatisfactory for diagnosing exanthema subitum.
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| Free Research Field |
臨床検査学
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