Risk factors for atrial fibrillation in a general Japanese population: the Hisayama Study

2016 Fiscal Year Final Research Report

• Project/Area Number: 26460748
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Kyushu University
• Principal Investigator: Jun Hata 九州大学, 医学研究院, 准教授 (00448432)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 心房細動 / 危険因子

Outline of Final Research Achievements

(1) Risk prediction model for the development of atrial fibrillation: A total of 2628 residents of Hisayama Town aged 40 years or over in 1988 were followed up for 14 years. In multivariable-adjusted model, older age, male sex, lower cholesterol, obesity, heart murmur, and electrocardiogram abnormalities were significantly and independently associated with the development of atrial fibrillation. We developed a risk prediction model for atrial fibrillation using these risk factors.
(2) Association of high-sensitivity CRP levels with the development of atrial fibrillation: Using 19-year follow-up data of this cohort, we investigated the association of serum levels of high-sensitivity CRP, a marker for chronic inflammation, with the risk of atrial fibrillation. Elevated CRP was a significant and independent risk factor for atrial fibrillation.

Free Research Field

疫学