2016 Fiscal Year Final Research Report
A surveillance of medical papers to correct inappropriate use of multivariate analysis and plan support for researchers
| Project/Area Number |
26460764
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 多変量解析 / 疫学 / 臨床疫学 / 医学統計 / 生物統計 / 統計専門家 |
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| Outline of Final Research Achievements |
While "multivariate analysis" is frequently used in medical research, it is currently difficult to say that sufficient understanding has advanced. Therefore, we decided to clarify the actual situation of implementation procedure in medical research paper published in academic journal. In this study, we focused on a method called "use only variables that were significant in univariate analysis" as an improper implementation procedure. The frequency was 8.6% for logistic regression and 9.8% for Cox regression. In addition, it was suggested that the risk of inappropriate methods being used increases when the department in which the first author belongs is not a specialized department such as epidemiology (clinical + other vs. epidemiology / public health department; the odds ratio is 5.6, 95% CI: 2.8 - 15.2).
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| Free Research Field |
臨床統計学
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