The development of molecular imaging on magnetic resonance for coronary atherosclerosis

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461119
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular medicine
• Research Institution: National Cardiovascular Center Research Institute
• Principal Investigator: Asaumi Yasuhide 国立研究開発法人国立循環器病研究センター, 病院, 医師 (20629315)
• Co-Investigator(Renkei-kenkyūsha): Noguchi Teruo 国立循環器病研究センター, 心臓血管内科, 部長 (70505099) ; Yasuda Satoshi 国立循環器病研究センター, 副院長 (00431578) ; Ueda Hatsue 国立循環器病研究センター, 病理部, 部長 (40522983)
• Research Collaborator: Morita Yoshiaki 国立循環器病研究センター, 放射線科, 室長 (80628074)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 核磁気共鳴画像法 / 冠動脈硬化 / 病理学

Outline of Final Research Achievements

I have shown the clinical significance of non-contrast T1 weighted magnetic resonance imaging for coronary atherosclerosis (e.g. percutanous coronary intervention, and medical treatments to visualize their status, the pathophysiology of coronary embolism and cardiac rupture in patients with acute myocardial infarction, and prognostic impact of percutaneous coronary intervention in patients with prior coronary artery bypass grafting during this period. In addition, we developed the large size animal model of coronary atherosclerosis. From this model, we will examine the role of vascular remodeling and its background in coronary atherosclerosis.

Free Research Field

循環器内科学