2016 Fiscal Year Final Research Report
Morphological diagnosis of injured podocytes in various renal diseases with proteinuria by low vacuum scanning electron microscopy
| Project/Area Number |
26461610
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Tottori University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
INAGA Sumire 鳥取大学, 医学部, 助教 (60116358)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 蛋白尿 / 糸球体上皮細胞 / 低真空走査型電子顕微鏡 |
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| Outline of Final Research Achievements |
We observed renal biopsy paraffin sections of various renal diseases patients by low vacuum scanning electron microscopy (LVSEM). The glomerular basement membranes showed characteristic coarse meshwork appearances in AS, and thin and sheet-like appearances in TBMN. Cyclosporin improved changes of foot processes of podocytes and alterations of podocytes cell bodies. Round-shaped podocytes cell bodies possibly represent injuries of podocytes in various renal diseases.
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| Free Research Field |
小児腎臓
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