Effect of transcranial direct current stimulation on cognitive function in schizophrenia

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461761
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: National Center of Neurology and Psychiatry
• Principal Investigator: Sumiyoshi Tomiki 国立研究開発法人国立精神・神経医療研究センター, トランスレーショナル・メディカルセンター, 部長 (80286062)
• Co-Investigator(Kenkyū-buntansha): 中込 和幸 国立研究開発法人国立精神・神経医療研究センター, その他部局等, 所長 (30198056)
• Co-Investigator(Renkei-kenkyūsha): OKAZAKI Mitsutoshi 国立研究開発法人国立精神・神経医療研究センター, 病院, 診療部長 (50568756) ; NODA Takamasa 国立研究開発法人国立精神・神経医療研究センター, 病院, 医長 (50446572) ; TAKAEDA Kazuyoshi 国立研究開発法人国立精神・神経医療研究センター, 病院, 医師 (00631342)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: ニューロモデュレーション / 経頭蓋直流刺激 / 統合失調症 / 認知機能障害

Outline of Final Research Achievements

This study investigated the effect of transcranial direct current stimulation on cognitive function in schizophrenia. Subjects were patients with schizophrenia who consented to participate in the study that was approved by Ethical Committee of NCNP. A tDCS apparatus of Soterix Medical Co.Ltd was used to stimulate the brain through electrodes place on left and right frontal cortex for 20 min, twice daily for 5 days. Cognition and psychotic symptoms were assessed before the stimulation and one month after the last stimulation. Repeated administration of tDCS was found to alleviate cognitive disturbances of patients with schizophrenia.

Free Research Field

生物学的精神医学