Diffusion Kurtosis Imaging of the Pancreas for the Assessement of HbA1c Levels

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461820
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Gifu University
• Principal Investigator: Noda Yoshifumi 岐阜大学, 医学部附属病院, 助教 (60643020)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 拡散尖度画像 / 糖尿病

Outline of Final Research Achievements

One-hundred-two patients underwent MR imaging included dufusion kurtosis imaging. Patients were classified into three groups using HbA1c values, HbA1c < 5.7% (group 1); 5.7% < HbA1c < 6.5% (group 2); and HbA1c > 6.5% (group 3). Radiologist measured the ADC and K values of the pancreas and compared among 3 groups.
Group 3 was significantly higher in K value than groups 1 and 2. The diagnostic performance for differentiating group 3 from groups 1 and 2 was superior compared with ADC value. These results suggest that the K value of the pancreas may be a better biomarker for grading pancreatic fibrosis and glucose intolerance than the ADC value.

Free Research Field

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