Bone and cartilage lesions of the wrist in rheumatoid arthritis: Evaluation by 3-Tesla high-resolution MR imaging

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461829
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Nagasaki University
• Principal Investigator: UETANI Masataka 長崎大学, 医歯薬学総合研究科(医学系), 教授 (40176582)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 関節リウマチ / MRI / CT / 手関節

Outline of Final Research Achievements

The purpose of this study is to clarify the utility of 3 Tesla high-resolution MR imaging of the wrist for demonstration of bone erosions and bone marrow edema (BME) in cases of rheumatoid arthritis (RA). High-resolution MR images precisely showed erosions in over 90% of joints, which were confirmed by high-resolution CT images. In follow-up MR studies, joints with BME showed progression to bone erosions more frequently than those without BME. The results provide an additional evidence that BME is a forerunner of bone erosion and progression in RA.

Free Research Field

放射線医学