2016 Fiscal Year Final Research Report
The development of tissue regeneration method using molecular biological chimeric induction and inhibitory cytokine
| Project/Area Number |
26461927
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Saitama Medical University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 気管軟骨移植 / 分子生物学的キメラ |
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| Outline of Final Research Achievements |
To induce immuno-tolerance, we tried to induce MHC Class 1 and 2 expression on recipient tissue to be molecular chimeric state. We chose tracheal cartilage and bile duct epithelia and succeeded in harvesting them and isolation and tissue transplantation, but we failed in induction of MHC Class 1 and 2. Therefore, we did not get any expected results.
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| Free Research Field |
小児腫瘍、移植免疫
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