2017 Fiscal Year Final Research Report
A role of the endocannabinoid system in a favorable recovery profile after propofol anesthesia
| Project/Area Number |
26462330
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Anesthesiology
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
|
| Keywords | propofol / anesthesia recovery / endocannabinoid system / cognitive function / emotional function |
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| Outline of Final Research Achievements |
Patients recovering from propofol anesthesia often report a feeling of well-being (pleasant) mood. Cannabinoids are one of the substances that can produce similar effect. We proposed and set out to test the hypothesis that the increase in endogenous cannabinoid concentration could be responsible for positive mood changing effect observed after propofol anesthesia. The results of this study suggest that endocannabinoid system may be involved in a positive affective state that is observed during the recovery from propofol anesthesia.
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| Free Research Field |
麻酔科学
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