Pathophysiological Changes in Platelet Function AND Morphofunctional Cardiac Changes in Pregnant Women

2016 Fiscal Year Final Research Report

• Project/Area Number: 26462468
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Obstetrics and gynecology
• Research Institution: Hokkaido University
• Principal Investigator: Yamada Takahiro 北海道大学, 医学研究科, 特任准教授 (20419948)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 周産期心筋症 / 妊娠高血圧 / 妊娠高血圧腎症 / 双胎妊娠 / 血小板機能

Outline of Final Research Achievements

Peripartum cardiomyopathy is a life-threatening pregnancy-associated cardiomyopathy with abrupt heart failure. At first, we established reference values for various echocardiographic parameters and biomarkers specific for trimesters of pregnancy and postpartum period. We also revealed the hemodynamic differences between normal pregnancy and hypertensive disorders of pregnancy or twin pregnancy. Finally, we proposed a new screening method by biomarkers in order to find in early stage of heart failure. These results will contribute to early detection and diagnosis of peripartum cardiomyopathy.

Free Research Field

周産期医学