Objective pathological diagnosis method of refractory temporomandibular disorders - Novel biomarker for central sensitization -

2017 Fiscal Year Final Research Report

• Project/Area Number: 26462955
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Keio University
• Principal Investigator: Muraoka Wataru 慶應義塾大学, 医学部(信濃町), 講師(非常勤) (70317254)
• Co-Investigator(Kenkyū-buntansha): 和嶋 浩一 慶應義塾大学, 医学部(信濃町), 講師(非常勤) (70138105)
• Research Collaborator: Usuda Syou
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 口腔顔面痛 / 顎関節症 / 中枢性感作 / 残感覚 / 時間的加重 / 熱刺激

Outline of Final Research Achievements

In order to apply the thermal stimulation protocol in a clinical setting for distinguishing the central sensitization in temporomandibular disorders, small device was newly developed which can distinguish central sensitization on equal terms with a conventional large-sized thermal stimulators.
It showed that small device for diagnosing central sensitization, and large-sized device did not have a difference about intra-class reliability and inter-class reliability.By using small device for diagnosing central sensitization, it was suggested that central sensitization could distinguish easily in a chair side.

Free Research Field

口腔顔面痛