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2016 Fiscal Year Final Research Report

The effect of ultraviolet functionalization of titanium on inflammation control

Research Project

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Project/Area Number 26462980
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionNihon University

Principal Investigator

TSUKIMURA Naoki  日本大学, 歯学部, 准教授 (10301558)

Co-Investigator(Renkei-kenkyūsha) ARAI Yoshinori  日本大学, 歯学部, 教授 (20212607)
Research Collaborator OGAWA Takahiro  
Project Period (FY) 2014-04-01 – 2017-03-31
Keywordsチタン / インプラント / オッセオインテグレーション / 紫外線 / マクロファージ
Outline of Final Research Achievements

In this present study, we evaluated the effect of UV treatment of titanium on the cellular reaction of macrophage. The amount of TNF-α in the supernatant of an untreated group was higher than that of UV treated group. In contrast, UV treatment increased the expression of IL-10 in the supernatant compared to untreated group. UV treatment decreased the number of CD48+ cells attached to titanium surface compared to the untreated surface. The results suggest that a surface alteration using UV-light treatment affect a cellular behavior of macrophage.

Free Research Field

歯科補綴学

URL: 

Published: 2018-03-22  

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