Establishment of jaw bone reconstruction treatment using osteoblast/interconnected porous hydroxyapatite ceramics composite

2016 Fiscal Year Final Research Report

• Project/Area Number: 26463009
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Hiroshima University
• Principal Investigator: masaaki takechi 広島大学, 医歯薬保健学研究院(歯), 准教授 (00304535)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: ｂｏｎｅ / ｈｙｄｒｏｘｙａｐａｔｉｔｅ

Outline of Final Research Achievements

We were able to establish the three-dimensional culture method of the most suitable human jaw bone of osteoblasts. In addition, as a result of making neobone that gave the jawbone form of dogs by CT image data, and having transplanted the complex with the cell after jaw bone area excision, good bone formation was observed in an experimental group in comparison with control group. Furthermostate，after implant placement,excellent osseointegration was provided in FGF-2 and the melatonin group.

Free Research Field

口腔外科学