2016 Fiscal Year Final Research Report
Influence of oral bacteria / fungus-producing acetaldehyde on oral burning mouse syndrome and establishment of therapy
| Project/Area Number |
26463030
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 口腔内灼熱症候群 / 口腔細菌・真菌産生 / アセトアルデヒド |
|---|
| Outline of Final Research Achievements |
In order to elucidate the pathogenesis of Burning mouse syndrome, we examined acetaldehyde production by oral bacteria / fungi and adverse effects on oral mucosa by acetaldehyde.
It was suggested that acetaldehyde was produced in the genus Candida which is an oral fungus and inhibition of epithelial differentiation marker of oral mucosal epithelial cells by acetaldehyde, so that acetaldehyde had an adverse effect on the oral mucosa.
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| Free Research Field |
口腔外科(口腔内科)学
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