2016 Fiscal Year Final Research Report
Pathogenesis research on oro-maxillary cytological proliferative lesions
| Project/Area Number |
26463031
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Matsumoto Dental University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 顎口腔 / 増殖性病変 / 多形腺腫 / 慢性炎症 / 細胞移動 / 細胞分化 / 骨髄間葉系細胞 / エナメル上皮腫 |
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| Outline of Final Research Achievements |
The results of the present research are done according to the points of cytological migration and differentiation in oral neoplasms (ameloblastomas and pleomorphic adenomas) and colonic inflammatory lesions, and the results lead to us to produce new methods for treatments of the lesions. They are as followings.
Cytological differentiation of odontogenic neoplasms and salivary neoplasms are related to the Wnt signaling and HSP expression. Furtheremore, The injury tissues of the periodontal ligament tissues due to orthodontic mechanical stress and occlusal traumatic stress are recovered due to immigrated bone marrow derived stromal cells and cytological differentiation into the tissue specific cells.
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| Free Research Field |
口腔病理学，硬組織疾患病態解析学
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